Telomere length and its associations with oxidized-LDL carotid artery distensibility and smoking
نویسندگان
چکیده
منابع مشابه
Telomere length and its associations with oxidized-LDL, carotid artery distensibility and smoking.
Oxidative stress is a key factor driving the aging of cells and arteries. Studies suggest that white blood cell (WBC) telomere length is an index of systemic aging. We, therefore, investigated the association between WBC telomere length and oxidized-LDL, and vascular aging, expressed by the distensibility of the carotid artery. We studied a random population sample of 216 non-smokers and 89, sm...
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OBJECTIVE To evaluate telomere length (TL) between patients with SLE and healthy controls and to test if TL is associated with carotid plaque. METHODS A pilot study of 154 patients with SLE and 152 controls was performed from the SOLVABLE (Study of Lupus Vascular and Bone Long-Term Endpoints) cohort. Demographic and cardiovascular disease (CVD) factors were collected at baseline. The presence...
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چکیده ندارد.
Heritability of Carotid Artery Distensibility in Hispanics
Background and Purpose—Reduced arterial distensibility has been introduced as a novel risk factor for atherosclerosis. The importance of the genetic contribution to variation in distensibility is largely unknown. The purpose of this study was to estimate heritability of carotid distensibility. Methods—The ongoing Northern Manhattan Family Study recruits high-risk Caribbean Hispanic families to ...
متن کاملAntibodies against oxidized LDL and carotid artery intima-media thickness in a healthy population.
Oxidation of LDLs plays an important role in atherosclerosis, and immune response to oxidized LDL (oxLDL) may modulate atherogenesis. Although immunization with oxLDL is shown to suppress atherogenesis in animal models, the role of the immune response to oxLDL is not well established in humans. We investigated the relationship between the titer of anti-oxLDL antibody (oxLDL Ab) and arterial wal...
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ژورنال
عنوان ژورنال: Frontiers in Bioscience
سال: 2010
ISSN: 1945-0494,1945-0508
DOI: 10.2741/e176